Bioinformatics Advance Access originally published online on March 3, 2005
Bioinformatics 2005 21(10):2539-2540; doi:10.1093/bioinformatics/bti360
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CoC: a database of universally conserved residues in protein folds
1Department of Chemistry and Chemical Biology, Harvard University 12 Oxford Street, Cambridge, MA 02138, USA
2Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology 77 Massachusetts Avenue, 16343, Cambridge, MA 02139, USA
*To whom correspondence should be addressed.
Summary: The conservatism of conservatism (CoC) database presents statistically analyzed information about the conservation of residue positions in folds across protein families.
Availability: On the web at http://kulibin.mit.edu/coc/
Contact: leonid{at}mit.edu
Supplementary information: The website details the method and contains an FAQ and documentation, http://kulibin.mit.edu/coc/