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Bioinformatics Advance Access originally published online on February 8, 2005
Bioinformatics 2005 21(10):2544-2545; doi:10.1093/bioinformatics/bti311
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© The Author 2005. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions{at}oupjournals.org

The Graphical Query Language: a tool for analysis of gene expression time-courses

Ivan G. Costa 1, Alexander Schönhuth 2 and Alexander Schliep 1,*

1Max Planck Institute for Molecular Genetics, Department of Computational Molecular Biology Ihnestrasse 73, 14195 Berlin, Germany
2Center for Applied Computer Science, University of Cologne Weyertal 80, 50937 Cologne, Germany

*To whom correspondence should be addressed.

Summary: The Graphical Query Language (GQL) is a set of tools for the analysis of gene expression time-courses. They allow a user to pre-process the data, to query it for interesting patterns, to perform model-based clustering or mixture estimation, to include subsequent refinements of clusters and, finally, to use other biological resources to evaluate the results. Analyses are carried out in a graphical and interactive environment, allowing expert intervention in all stages of the data analysis.

Availability: The GQL package is freely available under the GNU general public license (GPL) at http://www.ghmm.org/gql

Contact: schliep{at}molgen.mpg.de


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