Bioinformatics Advance Access originally published online on June 23, 2005
Bioinformatics 2005 21(16):3422-3423; doi:10.1093/bioinformatics/bti553
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ACT: the Artemis comparison tool
1Wellcome Trust Sanger Institute Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK
2Department of Genetics, University of Cambridge Downing Street, Cambridge, CB2 3EH, UK
*To whom correspondence should be addressed.
The Artemis Comparison Tool (ACT) allows an interactive visualisation of comparisons between complete genome sequences and associated annotations. The comparison data can be generated with several different programs; BLASTN, TBLASTX or Mummer comparisons between genomic DNA sequences, or orthologue tables generated by reciprocal FASTA comparison between protein sets. It is possible to identify regions of similarity, insertions and rearrangements at any level from the whole genome to base-pair differences. ACT uses Artemis components to display the sequences and so inherits powerful searching and analysis tools. ACT is part of the Artemis distribution and is similarly open source, written in Java and can run on any Java enabled platform, including UNIX, Macintosh and Windows.
Availability: ACT is freely available (under a GPL licence) for download from the Sanger Institute web site, http://www.sanger.ac.uk
Contact: artemis{at}sanger.ac.uk
Received on April 20, 2005; revised on June 7, 2005; accepted on June 22, 2005
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