Bioinformatics Advance Access originally published online on October 10, 2005
Bioinformatics 2005 21(23):4312-4314; doi:10.1093/bioinformatics/bti704
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ATID: a web-oriented database for collection of publicly available alternative translational initiation events

MOE Key Laboratory of Bioinformatics and Department of Automation, Tsinghua University Beijing 100084, China
*To whom correspondence should be addressed.
Summary: Alternative translational initiation is an important cellular mechanism contributing to the diversity of protein products and functions. We develop a database that provides a comprehensive collection of alternative translational initiation events. The purpose of this alternative translational initiation database (ATID) is to facilitate the systematic study of alternative translational initiation of genes. The current version of database contains 300 genes from Homo sapiens, Mus musculus and other species. Each of the genes has two or more isoforms due to alternative translational initiation. Resources in ATID, including gene information, alternative products of genes and domain structures of isoforms, are provided through a user-friendly web interface.
Availability: The ATID database is available for public use at http://bioinfo.au.tsinghua.edu.cn/atie/
Contact: caijun99{at}mails.tsinghua.edu.cn
Supplementary information: Supplementary instructions about this database and further statistical analyses can be found on the web page (http://bioinfo.au.tsinghua.edu.cn/atie/)
Received on June 5, 2005; revised on September 15, 2005; accepted on October 3, 2005