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Bioinformatics Advance Access originally published online on October 25, 2005
Bioinformatics 2005 21(24):4430-4431; doi:10.1093/bioinformatics/bti725
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© The Author 2005. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions{at}oxfordjournals.org

GSMA: software implementation of the genome search meta-analysis method

Fabio Pardi 1, Douglas F. Levinson 2 and Cathryn M. Lewis 1,*

1Department of Medical and Molecular Genetics, King's College London 8th Floor Guy's Tower, Guy's Hospital, London SE1 9RT, United Kingdom
2Division of Clinical Neurobiology and Behavior, University of Pennsylvania School of Medicine 3535 Market Street, Rm 4006, Philadelphia, PA 19104-3309, USA

*To whom correspondence should be addressed.

Meta-analysis can be used to pool results of genome-wide linkage scans. This is of great value in complex diseases, where replication of linked regions occurs infrequently. The genome search meta-analysis (GSMA) method is widely used for this analysis, and a computer program is now available to implement the GSMA.

Availability: http://www.kcl.ac.uk/depsta/memoge/gsma/

Contact: Cathryn.lewis{at}genetics.kcl.ac.uk


Received on August 11, 2005; revised on October 12, 2005; accepted on October 17, 2005

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