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Bioinformatics Advance Access originally published online on October 28, 2004
Bioinformatics 2005 21(7):1288-1290; doi:10.1093/bioinformatics/bti101
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© The Author 2004. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions{at}oupjournals.org

hp-DPI: Helicobacter pylori Database of Protein Interactomes—embracing experimental and inferred interactions

Chung-Yen Lin *, Chia-Ling Chen {dagger}, Chi-Shiang Cho , Li-Ming Wang , Chia-Ming Chang , Pao-Yang Chen , Chen-Zen Lo and Chao A. Hsiung

Division of Biostatistics and Bioinformatics, National Health Research Institutes #128, Sec. 2 Yaun-Chio-Yun Rd, Taipei 115, Taiwan

*To whom correspondence should be addressed.

Summary: We implemented a statistical model into our protein interaction database for validation of two-hybrid assays of Helicobacter pylori, and prediction of putative protein interactions not yet discovered experimentally. To present the enormous amount of experimental and inferred protein interaction networking maps, the H.pylori Database of Protein Interactomes (hp-DPI) is developed with a succinct yet comprehensive visualization tool integrated with annotation from Genbank, GO, and KEGG. hp-DPI is first built with, but not limited to, H.pylori protein interactions and is expected to naturally include other organisms’ protein interacting relationships in the future.

Availability: hp-DPI can be accessed at http://www.dpi.nhri.org.tw/hp/

Contact: cylin{at}nhri.org.tw


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Home page
 Nucleic Acids ResHome page
C.-Y. Lin, C.-H. Chin, H.-H. Wu, S.-H. Chen, C.-W. Ho, and M.-T. Ko
Hubba: hub objects analyzer--a framework of interactome hubs identification for network biology
Nucleic Acids Res., July 1, 2008; 36(suppl_2): W438 - W443.
[Abstract] [Full Text] [PDF]


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