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Bioinformatics Advance Access originally published online on December 14, 2004
Bioinformatics 2005 21(8):1703-1704; doi:10.1093/bioinformatics/bti222
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© The Author 2004. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions{at}oupjournals.org

CARHTA GENE: multipopulation integrated genetic and radiation hybrid mapping

Simon de Givry , Martin Bouchez , Patrick Chabrier , Denis Milan and Thomas Schiex *

INRA, Biométrie et Intelligence Artificielle/Génétique Cellulaire BP 27, 31326 Castanet-Tolosan Cedex, France

*To whom correspondence should be addressed.

Summary: CARHTA GENE: is an integrated genetic and radiation hybrid (RH) mapping tool which can deal with multiple populations, including mixtures of genetic and RH data. CARHTA GENE: performs multipoint maximum likelihood estimations with accelerated expectation–maximization algorithms for some pedigrees and has sophisticated algorithms for marker ordering. Dedicated heuristics for framework mapping are also included. CARHTA GENE: can be used as a C++ library, through a shell command and a graphical interface. The XML output for companion tools is integrated.

Availability: The program is available free of charge from www.inra.fr/bia/T/CarthaGene for Linux, Windows and Solaris machines (with Open Source).

Contact: tschiex{at}toulouse.inra.fr


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