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Bioinformatics Advance Access originally published online on December 14, 2004
Bioinformatics 2005 21(8):1713-1714; doi:10.1093/bioinformatics/bti208
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© The Author 2004. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions{at}oupjournals.org

GeneContent: software for whole-genome phylogenetic analysis

Xun Gu 1,2,*, Wei Huang 3, Dongping Xu 1 and Hongmei Zhang 4

1Department of Genetics, Development and Cell Biology, Iowa State University Ames, IA 50011, USA
2Center for Bioinformatics and Biological Statistics, Iowa State University Ames, IA 50011, USA
3Department of Electrical and Computer Engineering, Iowa State University Ames, IA 50011, USA
4Department of Mathematics and Statistics, University of West Florida Pensacola, FL 32514, USA

*To whom correspondence should be addressed.

Summary: GeneContent is a software system to infer the genome phylogeny based on an additive genome distance that can be estimated from the extended gene content data, which contains the genome-wide information (absence of a gene family, presence as single copy or presence as duplicates) across multiple species. GeneContent can also be used to explore the genome-wide evolutionary pattern of gene loss and proliferation.

Availability: Distribution packages of GeneContent for both Microsoft Windows and Linux operating systems are available at http://xgu.zool.iastate.edu

Contact: xgu{at}iastate.edu


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