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Bioinformatics Advance Access originally published online on September 11, 2006
Bioinformatics 2006 22(22):2819-2820; doi:10.1093/bioinformatics/btl466
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© The Author 2006. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Augur—a computational pipeline for whole genome microbial surface protein prediction and classification

A. Billion , R. Ghai , T. Chakraborty and T. Hain *

Institute of Medical Microbiology, Justus-Liebig-University Frankfurter Strasse 107, D-35392 Giessen, Germany

*To whom correspondence should be addressed.

Summary: The analysis of protein function is a challenge and a major bottleneck towards well-annotated and analysed microbial genomes. In particular, bacterial surface proteins present an opportunity for pharmacological intervention and vaccine development. We present Augur, an automatic prediction pipeline that integrates major surface prediction algorithms and enables comparative analysis, classification and visualization for gram-positive bacteria on a genomic scale.

Availability: http://bioinfo.mikrobio.med.uni-giessen.de/augur

Contact: Andre.Billion{at}mikrobio.med.uni-giessen.de

Supplementary information: Supplementary data are available at Bioinformatics online.

Received on July 26, 2006; revised on August 25, 2006; accepted on August 28, 2006

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