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Bioinformatics Advance Access originally published online on October 10, 2006
Bioinformatics 2006 22(22):2838-2840; doi:10.1093/bioinformatics/btl487
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© The Author 2006. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Integration of gel-based proteome data with pProRep

Kris Laukens 1,2,*, Rune Matthiesen 3, Filip Lemière 2, Eddy Esmans 2, Harry Van Onckelen 1,2, Ole Nørregaard Jensen 3 and Erwin Witters 1,2

1 Laboratory of Plant Physiology and Plant Biochemistry, University of Antwerp Groenenborgerlaan 171, B-2020 Antwerp, Belgium
2 CEPROMA, Center for Proteome Analysis and Mass Spectrometry, University of Antwerp Groenenborgerlaan 171, B-2020 Antwerp, Belgium
3 Department of Biochemistry & Molecular Biology, University of Southern Denmark Odense, Denmark

*To whom correspondence should be addressed.

Summary: pProRep is a web application integrating electrophoretic and mass spectral data from proteome analyses into a relational database. The graphical web-interface allows users to upload, analyse and share experimental proteome data. It offers researchers the possibility to query all previously analysed datasets and can visualize selected features, such as the presence of a certain set of ions in a peptide mass spectrum, on the level of the two-dimensional gel.

Availability: The pProRep package and instructions for its use can be downloaded from http://www.ptools.ua.ac.be/pProRep. The application requires a web server that runs PHP 5 (http://www.php.net) and MySQL. Some (non-essential) extensions need additional freely available libraries: details are described in the installation instructions.

Contact: kris.laukens{at}ua.ac.be

Received on March 29, 2006; revised on September 5, 2006; accepted on September 15, 2006

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