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Bioinformatics Advance Access originally published online on October 10, 2006
Bioinformatics 2006 22(23):2945-2947; doi:10.1093/bioinformatics/btl503
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© The Author 2006. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

ChromoScan: a scan statistic application for identifying chromosomal regions in genomic studies

Yan V. Sun *, Douglas M. Jacobsen and Sharon L. R. Kardia

Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor MI 48104-3028, USA

*To whom correspondence should be addressed.

Summary: ChromoScan is an implementation of a genome-based scan statistic that detects genomic regions, which are statistically significant for targeted measurements, such as genetic associations with disease, gene expression profiles, DNA copy number variations, as well as other genome-based measurements. A Java graphic user interface (GUI) is provided to allow users to select appropriate data transformations and thresholds for defining the significant events.

Availability: ChromoScan is freely available from http://www.epidkardia.sph.umich.edu/software/chromoscan/

Contact: yansun{at}umich.edu

Received on August 24, 2006; revised on September 28, 2006; accepted on September 30, 2006

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