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Bioinformatics Advance Access originally published online on January 17, 2006
Bioinformatics 2006 22(7):889-890; doi:10.1093/bioinformatics/btl007
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© The Author 2006. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Panta rhei (QAlign2): an open graphical environment for sequence analysis

Michael Sammeth , Thasso Griebel , Felix Tille and Jens Stoye *

Genome Informatics, Technical faculty, Bielefeld University PO Box 10 01 31, 33501 Bielefeld, Germany

*To whom correspondence should be addressed.

Motivation: The first version of the graphical multiple sequence alignment environment QAlign was published in 2003. Heavy response from the molecular-biological user community clearly demonstrated the need for such a platform.

Results: Panta rhei extends QAlign by several features. Major redesigns on the user interface, for instance, allow users to flexibily compose views for multiple projects. The new sequence viewer handles datasets with arbitrarily many and arbitrarily large sequences that may still be edited by guided block moving. More distance-based algorithms are available to interactively reconstruct phylogenetic trees which can now also be zoomed and navigated graphicaly.

Availability: Executables and the JAVA source code are available under the Apache license at http://gi.cebitec.uni-bielefeld.de/qalign

Contact: qalign{at}cebitec.uni-bielefeld.de

Received on December 4, 2005; revised on January 12, 2005; accepted on January 13, 2005

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