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Bioinformatics Advance Access originally published online on February 3, 2007
Bioinformatics 2007 23(7):901-902; doi:10.1093/bioinformatics/btm014
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© The Author 2007. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

DFprot: a webtool for predicting local chain deformability

José Ignacio Garzón 1, Julio Kovacs 2, Ruben Abagyan 2 and Pablo Chacón 1,*

1Centro de Investigaciones Biológicas, CSIC, Ramiro de Maeztu 9, 28040 Madrid, Spain and 2Department of Molecular Biology, The Scripps Research Institute La Jolla, California 92037, USA

*To whom correspondence should be addressed.


  Abstract

Summary: DFprot is a web-based server for predicting main-chain deformability from a single protein conformation. The server automatically performs a normal-mode analysis (NMA) of the uploaded structure and calculates its capability to deform at each of its residues. Non-specialists can easily and rapidly obtain a quantitative first approximation of the flexibility of their structures with a simple and efficient interface.

Availability: http://sbg.cib.csic.es/Software/DFprot

Contact: pablo{at}cib.csic.es

Associate Editor: Alfonso Valencia

Received on November 6, 2006; revised on January 11, 2007; accepted on January 14, 2007

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