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Bioinformatics Advance Access originally published online on June 13, 2008
Bioinformatics 2008 24(15):1743-1744; doi:10.1093/bioinformatics/btn285
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© 2008 The Author(s)
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

MPIDB: the microbial protein interaction database

Johannes Goll *, Seesandra V. Rajagopala , Shen C. Shiau , Hank Wu , Brian T. Lamb and Peter Uetz

The J. Craig Venter Institute, Rockville, MD 20850, USA

*To whom correspondence should be addressed.


  Abstract

Summary: The microbial protein interaction database (MPIDB) aims to collect and provide all known physical microbial interactions. Currently, 22 530 experimentally determined interactions among proteins of 191 bacterial species/strains can be browsed and downloaded. These microbial interactions have been manually curated from the literature or imported from other databases (IntAct, DIP, BIND, MINT) and are linked to 24 060 experimental evidences (PubMed ID, PSI-MI methods). In contrast to these databases, interactions in MPIDB are further supported by 8150 additional evidences based on interaction conservation, co-purification and 3D domain contacts (iPfam, 3did).

Availability: http://www.jcvi.org/mpidb/

Contact: jgoll{at}jcvi.org

Associate Editor: Jonathan Wren

Received on March 10, 2008; revised on June 6, 2008; accepted on June 8, 2008

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