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Bioinformatics Advance Access originally published online on October 7, 2008
Bioinformatics 2008 24(23):2773-2775; doi:10.1093/bioinformatics/btn517
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© The Author 2008. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

CNVDetector: locating copy number variations using array CGH data

Peng-An Chen 1, Hsiao-Fei Liu 1 and Kun-Mao Chao 1,2,3,*

1Department of Computer Science and Information Engineering, 2Graduate Institute of Biomedical Electronics and Bioinformatics and 3Graduate Institute of Networking and Multimedia, National Taiwan University, Taipei, Taiwan

*To whom correspondence should be addressed.


  Abstract

Summary: CNVDetector is a program for locating copy number variations (CNVs) in a single genome. CNVDetector has several merits: (i) it can deal with the array comparative genomic hybridization data even if the noise is not normally distributed; (ii) it has a linear time kernel; (iii) its parameters can be easily selected; (iv) it evaluates the statistical significance for each CNV calling.

Availability: CNVDetector (for Windows platform) can be downloaded from http:www.csie.ntu.edu.tw/~kmchao/tools/CNVDetector/. The manual of CNVDetector is also available.

Contact: kmchao{at}csie.ntu.edu.tw

Supplementary information: Supplementary data are available at Bioinformatics online.

Associate Editor: Alex Bateman

Received on March 12, 2008; revised on September 4, 2008; accepted on October 4, 2008

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F.-C. Chen, Y.-Z. Chen, and T.-J. Chuang
CNVVdb: a database of copy number variations across vertebrate genomes
Bioinformatics, June 1, 2009; 25(11): 1419 - 1421.
[Abstract] [Full Text] [PDF]


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