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Bioinformatics Advance Access originally published online on December 18, 2007
Bioinformatics 2008 24(3):438-439; doi:10.1093/bioinformatics/btm615
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© The Author 2007. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

ZFIQ: a software package for zebrafish biology

Tianming Liu 1,2, Jingxin Nie 1,2,3, Gang Li 1,2,3, Lei Guo 3 and Stephen T. C. Wong 1,2,*

1The Methodist Hospital Research Institute and Department of Radiology, The Methodist Hospital, 2Weill Cornell Medical College and 3School of Automation, Northwestern Polytechnic University, China

*To whom correspondence should be addressed.


  Abstract

Summary: Rapid development, transparency and small size are the outstanding features of zebrafish that make it as an increasingly important vertebrate system for developmental biology, functional genomics, disease modeling and drug discovery. Zebrafish has been regarded as ideal animal specie for studying the relationship between genotype and phenotype, for pathway analysis and systems biology. However, the tremendous amount of data generated from large numbers of embryos has led to the bottleneck of data analysis and modeling. The zebrafish image quantitator (ZFIQ) software provides streamlined data processing and analysis capability for developmental biology and disease modeling using zebrafish model.

Availability: ZFIQ is available for download at http://www.cbi-platform.net

Contact: STWong{at}tmhs.org

Supplementary information: Additional documentation for this software package is referred to http://www.cbi-platform.net/document.htm. Application examples of this software are referred to http://www.cbi-platform.net/download.htm

Associate Editor: Chris Stoeckert

Received on October 11, 2007; revised on December 10, 2007; accepted on December 10, 2007

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