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Bioinformatics Advance Access originally published online on January 17, 2008
Bioinformatics 2008 24(5):721-723; doi:10.1093/bioinformatics/btm494
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© The Author 2008. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

QTLNetwork: mapping and visualizing genetic architecture of complex traits in experimental populations

Jian Yang 1, Chengcheng Hu 2, Han Hu 1, Rongdong Yu 2, Zhen Xia 1, Xiuzi Ye 2 and Jun Zhu 1,*

1Institute of Bioinformatics, Zhejiang University, Hangzhou, China, 310029 and 2Computer Graphics and Imaging Laboratory, Zhejiang University, Hangzhou, China, 310027

*To whom correspondence should be addressed.


   Abstract

Summary: QTLNetwork is a software package for mapping and visualizing the genetic architecture underlying complex traits for experimental populations derived from a cross between two inbred lines. It can simultaneously map quantitative trait loci (QTL) with individual effects, epistasis and QTL–environment interaction. Currently, it is able to handle data from F2, backcross, recombinant inbred lines and double-haploid populations, as well as populations from specific mating designs (immortalized F2 and BCnFn populations). The Windows version of QTLNetwork was developed with a graphical user interface. Alternatively, the command-line versions have the facility to be run in other prevalent operating systems, such as Linux, Unix and MacOS.

Availability: http://ibi.zju.edu.cn/software/qtlnetwork

Contact: jzhu{at}zju.edu.cn

Associate Editor: Keith Crandall


Received on August 26, 2007; accepted on September 25, 2007

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