Skip Navigation


Bioinformatics Advance Access originally published online on April 9, 2009
Bioinformatics 2009 25(12):1561-1563; doi:10.1093/bioinformatics/btp185
This Article
Right arrow Full Text
Right arrow Full Text (Print PDF)
Right arrow Supplementary Data
Right arrow All Versions of this Article:
25/12/1561    most recent
btp185v1
Right arrow Comments: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when Comments are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Abney, M.
PubMed
Right arrow PubMed Citation
Right arrow Articles by Abney, M.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The Author 2009. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

A graphical algorithm for fast computation of identity coefficients and generalized kinship coefficients

Mark Abney

Department of Human Genetics, University of Chicago, 920 E 58th St., Chicago, IL 60637, USA


  Abstract

Summary: Computing the probability of identity by descent sharing among n genes given only the pedigree of those genes is a computationally challenging problem, if n or the pedigree size is large. Here, I present a novel graphical algorithm for efficiently computing all generalized kinship coefficients for n genes. The graphical description transforms the problem from doing many recursion on the pedigree to doing a single traversal of a structure referred to as the kinship graph.

Availability: The algorithm is implemented for n = 4 in the software package IdCoefs at http://home.uchicago.edu/abney/Software.html.

Contact: abney{at}bsd.uchicago.edu

Supplementary Information:Supplementary data are available at Bioinformatics online.

Associate Editor: Martin Bishop

Received on February 12, 2009; revised on March 30, 2009; accepted on March 31, 2009

Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.