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Bioinformatics Advance Access originally published online on May 19, 2009
Bioinformatics 2009 25(15):1994-1996; doi:10.1093/bioinformatics/btp330
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© 2009 The Author(s)
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

jClust: a clustering and visualization toolbox

Georgios A. Pavlopoulos 1,*,{dagger}, Charalampos N. Moschopoulos 2,{dagger}, Sean D. Hooper 3, Reinhard Schneider 1,*,{dagger} and Sophia Kossida 2,*,{dagger}

1 Structural and Computational Biology Unit, EMBL Meyerhofstrasse 1, Heidelberg, Germany, 2 Bioinformatics & Medical Informatics Team, Biomedical Research Foundation of the Academy of Athens, Soranou Efesiou 4, GR-11527, Athens, Greece and 3 Department of Energy Joint Genome Institute (DOE-JGI), Genome Biology Program, 2800 Mitchell Drive, Walnut Creek, CA 94598, US

* To whom correspondence should be addressed.


   Abstract

jClust is a user-friendly application which provides access to a set of widely used clustering and clique finding algorithms. The toolbox allows a range of filtering procedures to be applied and is combined with an advanced implementation of the Medusa interactive visualization module. These implemented algorithms are k-Means, Affinity propagation, Bron–Kerbosch, MULIC, Restricted neighborhood search cluster algorithm, Markov clustering and Spectral clustering, while the supported filtering procedures are haircut, outside–inside, best neighbors and density control operations. The combination of a simple input file format, a set of clustering and filtering algorithms linked together with the visualization tool provides a powerful tool for data analysis and information extraction.

Availability: http://jclust.embl.de/

Contact: pavlopou{at}embl.de; rschneid{at}embl.de; skossida{at}bioacademy.gr

Supplementary information: Supplementary data are available at Bioinformatics online.

{dagger} The authors wish it to be known that, in their opinion, the first two authors should be regarded as joint First Authors and the last two authors should be regarded as joint Last Authors.

Associate Editor: Jonathan Wren


Received on March 16, 2009; revised on April 27, 2009; accepted on May 15, 2009

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