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Bioinformatics Advance Access originally published online on August 28, 2009
Bioinformatics 2009 25(20):2745-2746; doi:10.1093/bioinformatics/btp518
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© The Author(s) 2009. Published by Oxford University Press.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

ANCHOR: web server for predicting protein binding regions in disordered proteins

Zsuzsanna Dosztányi *, Bálint Mészáros and István Simon

Institute of Enzymology, Biological Research Center, Hungarian Academy of Sciences, PO Box 7, H-1518 Budapest, Hungary

* To whom correspondence should be addressed.


  Abstract

Summary: ANCHOR is a web-based implementation of an original method that takes a single amino acid sequence as an input and predicts protein binding regions that are disordered in isolation but can undergo disorder-to-order transition upon binding. The server incorporates the result of a general disorder prediction method, IUPred and can carry out simple motif searches as well.

Availability: The web server is available at http://anchor.enzim.hu. The program package is freely available for academic users.

Contact: zsuzsa{at}enzim.hu

Associate Editor: Anna Tramontano

Received on June 25, 2009; revised on August 7, 2009; accepted on August 23, 2009

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