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Bioinformatics Advance Access originally published online on August 28, 2009
Bioinformatics 2009 25(22):3043-3044; doi:10.1093/bioinformatics/btp498
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© The Author 2009. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Next generation software for functional trend analysis

Gabriel F. Berriz 1, John E. Beaver 1, Can Cenik 1, Murat Tasan 1 and Frederick P. Roth 1,2,*

1Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, 250 Longwood Avenue and 2Center for Cancer Systems Biology, Dana Farber Cancer Institute, 44 Binney Street, Boston, MA 02115, USA

*To whom correspondence should be addressed.


  Abstract

Summary: FuncAssociate is a web application that discovers properties enriched in lists of genes or proteins that emerge from large-scale experimentation. Here we describe an updated application with a new interface and several new features. For example, enrichment analysis can now be performed within multiple gene- and protein-naming systems. This feature avoids potentially serious translation artifacts to which other enrichment analysis strategies are subject.

Availability: The FuncAssociate web application is freely available to all users at http://llama.med.harvard.edu/funcassociate.

Contact: fritz_roth{at}hms.harvard.edu

Associate Editor: Dmitrij Frishman

Received on June 29, 2009; revised on July 31, 2009; accepted on August 11, 2009

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