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© 1987 IRL Press Ltd.

HOMED: a homologous sequence editor

Peter A. Stockwell * and George B. Petersen

Department of Biochiemistry, University of Otago Box 56, Dunedin, New Zealand

*To whom reprint requests should be sent

The alignment of homologous sequences with each other and their display has proved a–difficult task, despite a frequent requirement for this process. HOMED enables related sequences to be edited and listed in parallel with each other. The editor function uses a full screen editor which emulates the text editors KED and EDT (on PDP–11 and VAX–11 respectively) and which can be adapted to emulate other text editors. This emulation has been adopted to simplify user learning of editing functions. HOMED provides functions for listing the sequences in a variety of formats and for generating a consensus sequence as well as providing a series of tools for maintenance of the sequence database. HOMED has been implemented in Pascal in a modular fashion to enhance portability.

Received on November 27, 1986; accepted on January 8, 1987

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