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© 1987 IRL Press Ltd.

Multiple sequence alignment by a pairwise algorithm

William Ramsay Taylor

Laboratory of Molecular Biology, Dept. of Crystallography, Birkbeck College London WC1E 7HX, UK

An algorithm is described that processes the results of a conventional pairwise sequence alignment program to automatically produce an unambiguous multiple alignment of many sequences. Unlike other, more complex, multiple alignment programs, the method described here is fast enough to be used on almost any multiple sequence alignment problem.


Received on September 25, 1986; accepted on January 29, 1987

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