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© IRL Press Limited

A new interactive protein sequence alignment program and comparison of its results with widely used algorithms

Renas Rechid , Martin Vingron and Patrick Argos *

European Molecular Biology Laboratory Postfach 10,2209, Meyerhofstrasse 1, 6900 Heidelberg, FRG

*To whom reprint requests should be sent

A computer program that allows interactive sequence comparison is described. It graphically displays a search matrix using residue physicochemical characteristics and multilength segmental comparisons. The user selects through a mousing device and screen pointer the sequence spans to be matched. The results of this method are compared with those of ALIGN and BESTFIT.

Received on August 23, 1988; accepted on December 6, 1988

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