Skip Navigation

This Article
Right arrow Full Text (Print PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Cheminant, M.
Right arrow Articles by Labia, R.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Cheminant, M.
Right arrow Articles by Labia, R.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© IRL Press

The Michaelis — Menten equation: computing substrate concentration as a function of time without restrictions on the initial conditions

Michel Cheminant and Roger Labia 1

Muséum National d'Histoire Naturelle, URA 401 CNRS 63 rue Buffon, 75005 Paris, France

1To whom correspondence should be addressed

We describe a novel algorithm for enzyme kinetics following the Michaelis-Menten equation, with the particular aim of computing the substrate concentration as a function of time without restrictions on the initial conditions. This algorithm, named ‘tangent exponential’ was demonstrated to converge for all initial conditions when the initial substrate concentration is positive. When the data are close to the solution, a quadratic convergence was demonstrated.

Received on June 13, 1990; accepted on October 9, 1990

Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.