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© IRL Press

Compositional variations in DNA sequences

Ruth Nussinov

Laboratory of Mathematical Biology, Bldg. 10, Rm. 4B-56, NCI, NIH Bethesda, MD 20892, USA Sackler Institute of Molecular Medicine, Faculty of Medicine, Tel Aviv University Ramat Aviv, Israel

Biologically occurring nucleotide sequences differ from randomly generated ones. Here we describe general patterns found in prokaryotic and in eukaryotic DNA. In the accompanying paper (Nussinov, 1991) we also describe DNA signals recognized by their corresponding protein factors. In particular, we focus on modes of searches for such patterns and signals and on the potential properties such sequences may possess.


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