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© Oxford University Press

MULTICOMP: a program package for multiple sequence comparison

Mauno Vihinen , Antti Euranto 1, Petri Luostarinen 1 and Olli Nevalainen 1

Department of Biochemistry and Centre for Biotechnology, University of Turku SF-20500 Turku, Finland
1Department of Computer Science. University of Turku SF-20500 Turku, Finland

An algorithm for multiple sequence comparison was implemented in FORTRAN 77 for VAX/VMS in GCG-atible format. The MULTICOMP program package includes several procedures with which one query sequence can be compared simultaneously to several DNA, RNA or amino acid sequences. The same technique was also introduced for comparing propensities of secondary structural features, which can be predicted on the basis of amino acid sequences. The technique has been applied to a wide range of sequence and structural analyses.

Received on April 16, 1991; accepted on July 31, 1991

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