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© Oxford University Press

A dotplot program for the Atari ST, for the analysis of DNA and protein sequences

C. Karreman

Department of Paediatrics Building 12, Academic Hospital Leiden PO Bax 9600, 2300 RC Leiden, The Netherlands

A program was written in GFA-BASIC for the Atari ST microcomputer aimed at drawing two-dimensional homology ‘dotplot’ patterns for two protein or DNA sequences. The program, built around a machine-code subroutine, communicates interactively with the user by means of a multi-button dialogue panel and mouse-directed input. A 1000 x 1000 sequence comparison with a 14: 21 stringency window takes 12 s.

Received on April 9, 1991; accepted on June 5, 1991

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