Bioinformatics Advance Access originally published online on February 10, 2009
Bioinformatics 2009 25(7):971-973; doi:10.1093/bioinformatics/btp079
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STEM: species tree estimation using maximum likelihood for gene trees under coalescence
1Departments of Statistics and Evolution, Ecology, and Organismal Biology, The Ohio State University, Columbus, OH 43210, 2Department of Biological Sciences, Louisiana State University, Baton Rouge, LA 70803 and 3Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, MI 48109, USA
*To whom correspondence should be addressed.
| Abstract |
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Summary: STEM is a software package written in the C language to obtain maximum likelihood (ML) estimates for phylogenetic species trees given a sample of gene trees under the coalescent model. It includes options to compute the ML species tree, search the space of all species trees for the k trees of highest likelihood and compute ML branch lengths for a user-input species tree.
Availability: The STEM package, including source code, is freely available at http://www.stat.osu.edu/~lkubatko/software/STEM/.
Contact: lkubatko{at}stat.osu.edu
Supplementary information: Supplementary data are available at Bioinformatics online.
Associate Editor: Martin Bishop
Received on November 28, 2008; revised on February 4, 2009; accepted on February 4, 2009
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