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Bioinformatics Advance Access originally published online on July 3, 2009
Bioinformatics 2009 25(20):2755-2757; doi:10.1093/bioinformatics/btp408
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© The Author(s) 2009. Published by Oxford University Press.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

FBA-SimVis: interactive visualization of constraint-based metabolic models

Eva Grafahrend-Belau 1,*, Christian Klukas 1, Björn H. Junker 1 and Falk Schreiber 1,2

1Leibniz-Institute of Plant Genetics and Crop Plant Research (IPK) Gatersleben and 2Institute of Computer Science, Martin-Luther-University Halle-Wittenberg, Germany

*To whom correspondence should be addressed.


  Abstract

Summary: FBA-SimVis is a VANTED plug-in for the constraint-based analysis of metabolic models with special focus on the visual exploration of metabolic flux data resulting from model analysis. The program provides a user-friendly environment for model reconstruction, constraint-based model analysis, and interactive visualization of the simulation results. With the ability to quantitatively analyse metabolic fluxes in an interactive and visual manner, FBA-SimVis supports a comprehensive understanding of constraint-based metabolic flux models in both overview and detail.

Availability: Software with manual and tutorials are freely available at http://fbasimvis.ipk-gatersleben.de/

Contact: grafahr{at}ipk-gatersleben.de

Supplementary information: Examples and supplementary data are available at http://fbasimvis.ipk-gatersleben.de/

Associate Editor: John Quackenbush

Received on March 1, 2009; revised on June 24, 2009; accepted on June 28, 2009

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