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It is time to end the patenting of software
1 Department of Biostatistics, Dana-Farber Cancer Institute, Harvard School of Public Health Boston, MA 02115, USA. E-mail: johnq@jimmy.harvard.edu.
2 Center for Bioinformatics and Computational Biology, University of Maryland College Park, MD 20742, USA E-mail: salzberg@umd.edu.
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One of the most significant outcomes of genomics has been a rapid increase in the rate that we as a community can generate data on interesting biological systems. Rapid improvements in technologies such as DNA microarrays and proteomics applications have produced a climate where the challenge is no longer collecting high quality data but rather managing and analyzing it. As we in the bioinformatics community have addressed this challenge, we have had to carefully consider the way in which the results of our intellectual effortsthe software tools that we developare made available to the wider research community. Increasingly, bioinformatics scientists are coming to call for development in an open source environment in which software is distributed with its underlying source code