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© Oxford University Press

qValue-A program to calculate comparative measures of genomic reorganisation from cytogenetic and/or linkage information

Andrew S. Law 1 and David W. Burt

Division of Molecular Biology, Roslin Institute (Edinburgh) Midlothian, EH25 9PS. Scotland

1To whom correspondence should be addressed. E-mail:Andy.Law{at}bbsrc.ac.uk

A program qValue, which calculates a measure of the genomic reorganisation that has occurred between pairs of species since their divergence from a common ancestor, is described. The program takes a tab-delimited text file containing data describing the location of various genetic loci in multiple species and generates an output text file, also in tab-delimited format, that lists various parameters of genomic reorganisation between all possible pairs of species considered. This provides a useful tool for the developing field of comparative genome mapping, particularly in the study of the evolution of the vertebrate genome.

Received on October 17, 1995; accepted on February 8, 1996

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