Bioinformatics, Vol 14, 617-623, Copyright © 1998 by Oxford University Press
K Mizuguchi, CM Deane, TL Blundell, MS Johnson and JP Overington
MOTIVATION: JOY is a program to annotate protein sequence alignments with
three-dimensional (3D) structural features. It was developed to display 3D
structural information in a sequence alignment and to help understand the
conservation of amino acids in their specific local environments. RESULTS::
The JOY representation now constitutes an essential part of the two
databases of protein structure alignments: HOMSTRAD
(http://www-cryst.bioc.cam.ac.uk/~homstrad ) and CAMPASS
(http://www-cryst.bioc.cam.ac. uk/~campass). It has also been successfully
used for identifying distant evolutionary relationships. AVAILABILITY: The
program can be obtained via anonymous ftp from torsa.bioc.cam.ac.uk from
the directory /pub/joy/. The address for the JOY server is
http://www-cryst.bioc.cam.ac.uk/cgi-bin/joy.cgi. CONTACT:
kenji@cryst.bioc.cam.ac.uk
ARTICLES
JOY: protein sequence-structure representation and analysis
Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge CB2 1GA, UK. kenji@cryst.bioc.cam.ac.uk
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