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Bioinformatics Vol. 16 no. 8 2000
Pages 739-740
© 2000 Oxford University Press

Applications Note

TRES: comparative promoter sequence analysis

Mukund V. Katti 1, Meena K. Sakharkar 2, Prabhakar K. Ranjekar 1 and Vidya S. Gupta 1,***

1 Plant Molecular Biology Unit, Division of Biochemical Sciences, National Chemical Laboratory, Pune 411 008, INDIA
2 Bioinformatics Centre, National University of Singapore, Singapore

Received on February 9, 2000 ; revised on March 30, 2000 ; accepted on April 12, 2000

Summary: Comparative promoter analysis is a promising strategy for elucidation of common regulatory modules conserved in evolutionarily related sequences or in genes showing common expression profiles. To facilitate such analysis, we have developed a software tool that detects conserved transcription factor binding sites, cis-elements, palindromes and k-tuples simultaneously in a set of sequences, and thus helps to identify putative motifs for designing further experiments.

Availability: The program TRES can be accessed at URL: http://www.bic.nus.edu.sg:8888/tres

Contact: vidya{at}ems.ncl.res.in

*** To whom correspondance should be addressed Vidya S. Gupta, Division of Biochemical Sciences, National Chemical Laboratory, Pune-411 008, INDIA


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