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Bioinformatics Vol. 17 no. 12 2001
Pages 1152-1157
© 2001 Oxford University Press

Differential expression of genes coding for ribosomal proteins in different human tissues

S. Bortoluzzi 1, F. d’Alessi 1, C. Romualdi 2 and G. A. Danieli 1,*

1 Department of Biology
2 CRIBI Biotechnology Centre, University of Padua, Via G. Colombo 3, 35131, Italy

Received on March 2, 2001 ; revised on June 1, 2001 ; accepted on June 5, 2001

Motivation: To perform a computational and statistical study on a large set of gene expression data pertaining six adult human tissues (brain, liver, skeletal muscle, ovary, retina and uterus) for analyzing the expression of ribosomal protein genes.

Results: Unexpectedly, in each of the considered tissues large variations in the expression of ribosomal protein genes were observed. Moreover, when comparing the expression levels of 89 ribosomal protein genes in six different tissues, 13 genes appeared differentially expressed among tissues.

Avalilability: The expression data of the ribosomal protein genes together with supplementary material (complete transcriptional profiles of the considered human tissues) are freely available at the site GETProfiles (http://telethon.bio.unipd.it/GETProfiles/).

Contact: danieli{at}bio.unipd.it

* To whom all correspondence should be addressed.


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