Bioinformatics Vol. 17 no. 8 2001
Pages 738-739
© 2001 Oxford University Press
Applications Note |
Genotype transposer: automated genotype manipulation for linkage disequilibrium analysis
Genome Analysis Group, International Agency for Research on Cancer, 69008 Lyon, France
Received on March 26, 2001
; revised on April 25, 2001
; accepted on April 25, 2001
Summary: The purpose of this work is to provide the modern molecular geneticist with tools to perform more efficient and more accurate analysis of the genotype data they produce. By using Microsoft Excel macros written in Visual Basic, we can translate genotype data into a form readable by the versatile software ‘Arlequin’, read the Arlequin output, calculate statistics of linkage disequilibrium, and put the results in a format for viewing with the software ‘GOLD’.
Availability: The software is available by FTP at: ftp://xcsg.iarc.fr/cox/Genotype_Transposer/.
Contact: cox{at}iarc.fr
Supplementary information: Detailed instruction and examples are available at: ftp://xcsg.iarc.fr/cox/Genotype&_Transposer/. Arlequin is available at: http://lgb.unige.ch/arlequin/. GOLD is available at: http://www.well.ox.ac.uk/asthma/GOLD/.
* To whom correspondence should be addressed.
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