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Bioinformatics Vol. 18 no. 7 2002
Pages 934-938
© 2002 Oxford University Press

About the use of protein models

Manuel C. Peitsch 1,2

1 Novartis Pharma AG, WKL-490.4.04, 4002 Basel, Switzerland
2 Swiss Institute of Bioinformatics, Chemin des Boveresses 155, 1066 Epalinges, Switzerland

Received on June 4, 2001 ; revised on November 20, 2001 ; accepted on December 15, 2001

Protein models can be of great assistance in functional genomics, as they provide the structural insights often necessary to understand protein function. Although comparative modelling is far from yielding perfect structures, this is still the most reliable method and the quality of the predictions is now well understood. Models can be classified according to their correctness and accuracy, which will impact their applicability and usefulness in functional genomics and a variety of situations.

Contact: manuel.peitsch{at}pharma.novartis.com; manuel.peitsch{at}isb-sib.ch


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