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Bioinformatics Vol. 19 no. 16 2003
pages 2152-2154
© 2003 Oxford University Press

Applications Note

RED-T: utilizing the Ratios of Evolutionary Distances for determination of alternative phylogenetic events

Kamyar Farahi 1, William B. Whitman 1,* and Eileen T. Kraemer 2

1 Department of Microbiology and 2 Computer Science Department, The University of Georgia, Athens, GA 30602, USA

Received on November 11, 2002 ; revised on March 24, 2003 ; accepted on March 28, 2003

Summary: RED-T is a Java application for phylogenetic analysis based on a unique method, RED, that utilizes the ratios of evolutionary distances Ed to distinguish between alternative evolutionary histories. RED-T allows the user to examine if any given experimental gene shares the same evolutionary history as the designated control gene(s). Moreover, the tool detects any differences in evolutionary history and allows the user to examine comparisons of Ed for a likely explanation. Lateral gene transfer, which may have a significant influence in organismal evolution is one mechanism that could explain the findings of these RED-T analyses.

Availability: The application is available online at http://www.arches.uga.edu/~whitman/RED.

Contact: whitman{at}arches.uga.edu

* To whom correspondence should be addressed.


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