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Bioinformatics Vol. 19 no. 16 2003
pages 2158-2160
© 2003 Oxford University Press


Applications Note

GARBAN: genomic analysis and rapid biological annotation of cDNA microarray and proteomic data

Luis A. Martínez-Cruz 1,§, Angel Rubio 2,§, María L. Martínez-Chantar 1, Alberto Labarga 2, Isabel Barrio 2, Adam Podhorski 2, Victor Segura 2, José L. Sevilla Campo 2, Matías A. Avila 1 and Jose M. Mato 1,*

1 Department of Internal Medicine, Unit of Proteomics, Genomics and Bioinformatics, University of Navarra, Pamplona-31008, Spain and 2 Centro de Estudios e Investigaciones Tecnológicas de Guipúzcoa (CEIT), San Sebastián, Spain

Received on February 14, 2003 ; revised on May 9, 2003 ; accepted on May 16, 2003

Summary: Genomic Analysis and Rapid Biological ANnotation (GARBAN) is a new tool that provides an integrated framework to analyze simultaneously and compare multiple data sets derived from microarray or proteomic experiments. It carries out automated classifications of genes or proteins according to the criteria of the Gene Ontology Consortium at a level of depth defined by the user. Additionally, it performs clustering analysis of all sets based on functional categories or on differential expression levels. GARBAN also provides graphical representations of the biological pathways in which all the genes/proteins participate.

Availability: http://garban.tecnun.es

Contact: jmmato{at}unav.es

* To whom correspondence should be addressed.

§ The authors wish it to be known that, in their opinion, the first two authors should be regarded as joint First Authors.


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