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Bioinformatics Vol. 19 no. 18 2003
pages 2496-2497
© 2003 Oxford University Press


Applications Note

DnaSP, DNA polymorphism analyses by the coalescent and other methods

Julio Rozas 1,*, Juan C. Sánchez-DelBarrio 2,{dagger}, Xavier Messeguer 2 and Ricardo Rozas 1

1 Departament de Genètica, Facultat de Biologia, Universitat de Barcelona, Diagonal 645, 08071 Barcelona, Spain and 2 Departament de Llenguatges i Sistemes Informàtics, Universitat Politècnica de Catalunya, Barcelona, Spain

Received on February 28, 2003 ; revised on June 6, 2003 ; accepted on July 8, 2003

Summary: DnaSP is a software package for the analysis of DNA polymorphism data. Present version introduces several new modules and features which, among other options allow: (1) handling big data sets (~5 Mb per sequence); (2) conducting a large number of coalescent-based tests by Monte Carlo computer simulations; (3) extensive analyses of the genetic differentiation and gene flow among populations; (4) analysing the evolutionary pattern of preferred and unpreferred codons; (5) generating graphical outputs for an easy visualization of results.

Availability: The software package, including complete documentation and examples, is freely available to academic users from: http://www.ub.es/dnasp

Contact: jrozas{at}ub.edu

* To whom correspondence should be addressed.

{dagger} Present address: Departament de Tecnología, Universitat Pompeu Fabra, Barcelona, Spain.


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