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Bioinformatics Vol. 19 no. 5 2003
Pages 673-674
© 2003 Oxford University Press

Applications Note

DomCut: prediction of inter-domain linker regions in amino acid sequences

Mikita Suyama 1,*,{dagger} and Osamu Ohara 1,2

1 Laboratory of DNA Technology, Kazusa DNA Research Institute, 1532-3 Yana, Kisarazu, Chiba 292-0812, Japan
2 Immunogenomics, RIKEN Research Center for Allergy and Immunology, RIKEN Yokohama Institute, 1-7-22, Suehiro-cho, Tsurumi, Yokohama, Kanagawa, Japan

Received on May 27, 2002 ; revised on September 18, 2002 ; accepted on October 25, 2002

Summary: DomCut is a program to predict inter-domain linker regions solely by amino acid sequence information. The prediction is made by using linker index deduced from a data set of domain/linker segments. The linker preference profile, which is the averaged linker index along a sequence, can be visualized in the graphical interface.

Availability: The web server, together with supplementary information, is available at http://www.kazusa.or.jp/tech/suyama/domcut. The distribution version of DomCut is also available upon request from the authors.

Contact: suyama{at}embl-heidelberg.de

* To whom correspondence should be addressed.

{dagger} Present address: Biocomputing, EMBL, Meyerhofstrasse 1, 69012 Heidelberg, Germany.


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