Skip Navigation

This Article
Right arrow FREE Full Text (Print PDF) Freely available
Right arrow FREE Full Text (Screen PDF)
Right arrow Comments: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when Comments are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (34)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Singh, H.
Right arrow Articles by Raghava, G.P.S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Singh, H.
Right arrow Articles by Raghava, G.P.S.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Bioinformatics Vol. 19 no. 8 2003
Pages 1009-1014
© 2003 Oxford University Press

ProPred1: prediction of promiscuous MHC Class-I binding sites

Harpreet Singh and G.P.S. Raghava *

Institute of Microbial technology, Chandigarh 160036, India

Received on July 18, 2002 ; revised on July 18, 2002 ; accepted on January 3, 2003

Summary: ProPred1 is an on-line web tool for the prediction of peptide binding to MHC class-I alleles. This is a matrix-based method that allows the prediction of MHC binding sites in an antigenic sequence for 47 MHC class-I alleles. The server represents MHC binding regions within an antigenic sequence in user-friendly formats. These formats assist user in the identification of promiscuous MHC binders in an antigen sequence that can bind to large number of alleles. ProPred1 also allows the prediction of the standard proteasome and immunoproteasome cleavage sites in an antigenic sequence. This server allows identification of MHC binders, who have the cleavage site at the C terminus. The simultaneous prediction of MHC binders and proteasome cleavage sites in an antigenic sequence leads to the identification of potential T-cell epitopes.

Availability: Server is available at http://www.imtech.res.in/raghava/propred1/. Mirror site of this server is available at http://bioinformatics.uams.edu/mirror/propred1/

Supplementary information: Matrices and document on server are available at http://www.imtech.res.in/raghava/propred1/page2.html

Contact: raghava{at}imtech.res.in

* To whom correspondence should be addressed at Bioinformatics Centre, Institute of Microbial Technology, Sector 39A, Chandigarh, India.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Proc. Natl. Acad. Sci. USAHome page
H. Xin, S. Dziadek, D. R. Bundle, and J. E. Cutler
Synthetic glycopeptide vaccines combining {beta}-mannan and peptide epitopes induce protection against candidiasis
PNAS, September 9, 2008; 105(36): 13526 - 13531.
[Abstract] [Full Text] [PDF]

Home page
 CVIHome page
A. Geluk, J. van der Ploeg, R. O. B. Teles, K. L. M. C. Franken, C. Prins, J. W. Drijfhout, E. N. Sarno, E. P. Sampaio, and T. H. M. Ottenhoff
Rational Combination of Peptides Derived from Different Mycobacterium leprae Proteins Improves Sensitivity for Immunodiagnosis of M. leprae Infection
Clin. Vaccine Immunol., March 1, 2008; 15(3): 522 - 533.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Cell Mol. Bio.Home page
J. Figueredo, M. P. Limberis, and J. M. Wilson
Prediction of Cellular Immune Responses against CFTR in Patients with Cystic Fibrosis after Gene Therapy
Am. J. Respir. Cell Mol. Biol., May 1, 2007; 36(5): 529 - 533.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
S. Saha and G. P. S. Raghava
AlgPred: prediction of allergenic proteins and mapping of IgE epitopes.
Nucleic Acids Res., July 1, 2006; 34(Web Server issue): W202 - W209.
[Abstract] [Full Text] [PDF]

Home page
 J. Virol.Home page
K. A. Herd, S. Mahalingam, I. M. Mackay, M. Nissen, T. P. Sloots, and R. W. Tindle
Cytotoxic T-Lymphocyte Epitope Vaccination Protects against Human Metapneumovirus Infection and Disease in Mice
J. Virol., February 15, 2006; 80(4): 2034 - 2044.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
J. M. Calvo-Calle, G. A. Oliveira, and E. H. Nardin
Human CD4+ T Cells Induced by Synthetic Peptide Malaria Vaccine Are Comparable to Cells Elicited by Attenuated Plasmodium falciparum Sporozoites
J. Immunol., December 1, 2005; 175(11): 7575 - 7585.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
K. E. Griswold, Y. Kawarasaki, N. Ghoneim, S. J. Benkovic, B. L. Iverson, and G. Georgiou
Evolution of highly active enzymes by homology-independent recombination
PNAS, July 19, 2005; 102(29): 10082 - 10087.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
E. M. Sigurdsson, E. Knudsen, A. Asuni, C. Fitzer-Attas, D. Sage, D. Quartermain, F. Goni, B. Frangione, and T. Wisniewski
An Attenuated Immune Response Is Sufficient to Enhance Cognition in an Alzheimer's Disease Mouse Model Immunized with Amyloid-{beta} Derivatives
J. Neurosci., July 14, 2004; 24(28): 6277 - 6282.
[Abstract] [Full Text] [PDF]

Home page
 Infect. Immun.Home page
A. Diaz-Quinonez, N. Martin-Orozco, A. Isibasi, and V. Ortiz-Navarrete
Two Salmonella OmpC Kb-Restricted Epitopes for CD8+-T-Cell Recognition
Infect. Immun., May 1, 2004; 72(5): 3059 - 3062.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.