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Bioinformatics Advance Access originally published online on March 25, 2004
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Bioinformatics 20(13) © Oxford University Press 2004; all rights reserved.

Applications Note

The DISOPRED server for the prediction of protein disorder

Jonathan J. Ward , Liam J. McGuffin , Kevin Bryson , Bernard F. Buxton and David T. Jones *

Bioinformatics Group, Department of Computer Science, University College London, Gower Street, London, WC1E 6BT, UK

Received on February 19, 2004; accepted on March 20, 2004
Advance Access Publication March 25, 2004

Summary: Dynamically disordered regions appear to be relatively abundant in eukaryotic proteomes. The DISOPRED server allows users to submit a protein sequence, and returns a probability estimate of each residue in the sequence being disordered. The results are sent in both plain text and graphical formats, and the server can also supply predictions of secondary structure to provide further structural information.

Availability: The server can be accessed by non-commercial users at http://bioinf.cs.ucl.ac.uk/disopred/

Contact: dtj{at}cs.ucl.ac.uk

* To whom correspondence should be addressed.


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