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Bioinformatics Advance Access originally published online on April 1, 2004
Bioinformatics 2004 20(14):2315-2316; doi:10.1093/bioinformatics/bth224
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Bioinformatics 20(14) © Oxford University Press 2004; all rights reserved.

Applications Note

PedSplit: pedigree management for stratified analysis

M. B. Lanktree 1,*, L. VanderBeek 1, F. M. Macciardi 1,2 and J. L. Kennedy 1

1 Neurogenetics Section, Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, 250 College Street, Toronto M5T 1R8, Canada and 2 Department of Human Genetics, University of Milan, Italy

Received on January 26, 2004; accepted on February 16, 2004
Advance Access Publication April 1, 2004

Summary: PedSplit facilitates pedigree management for gene–gene interaction and sex specific tests for increased homogeneity within subgroups. PedSplit also provides a simple approach for calculating haplotype relative risk and generating internal ‘controls’.

Availability: Executables, C++ source code and documentation for PedSplit can be downloaded from http://www.pharmacogenetics.ca in the links and software section.

Contact: Matthew_Lanktree{at}camh.net

* To whom correspondence should be addressed.


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