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Bioinformatics Advance Access originally published online on July 9, 2004
Bioinformatics 2004 20(18):3656-3658; doi:10.1093/bioinformatics/bth401
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Bioinformatics vol. 20 issue 18 © Oxford University Press 2004; all rights reserved.

Applications Note

DNMAD: web-based diagnosis and normalization for microarray data

Juan M. Vaquerizas , Joaquín Dopazo and Ramón Díaz-Uriarte *

Bioinformatics Unit, CNIO, Spanish National Cancer Centre, Melchor Fernández Almagro 3, 28029 Madrid, Spain

; revised on May 31, 2004; accepted on July 1, 2004
Advance Access Publication July 9, 2004

Summary: We present a web server for Diagnosis and Normalization of MicroArray Data (DNMAD). DNMAD includes several common data transformations such as spatial and global robust local regression or multiple slide normalization, and allows for detecting several kinds of errors that result from the manipulation and the image analysis of the arrays. This tool offers a user-friendly interface, and is completely integrated within the Gene Expression Pattern Analysis Suite (GEPAS).

Availability: The tool is accessible on-line at http://dnmad.bioinfo.cnio.es

Contact: rdiaz{at}cnio.es

* To whom correspondence should be addressed.


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