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Bioinformatics Advance Access originally published online on February 10, 2004
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Bioinformatics 20(8) © Oxford University Press 2004; all rights reserved.

Applications Note

2LD, GENECOUNTING and HAP: computer programs for linkage disequilibrium analysis

Jing Hua Zhao

Department of Epidemiology and Public Health, University College London, 1-19 Torrington Place, London WC1E 6BT, UK

Received on August 31, 2003; revised on November 7, 2003; accepted on November 17, 2003
Advance Access Publication February 10, 2004

Summary: Computer programs are introduced which calculate pair-wise linkage disequilibrium statistics and conduct haplotype frequency estimation, including X chromosome data, and using a heuristic algorithm to handle multiple genetic markers and missing data.

Availability: Programs 2LD, GENECOUNTING and HAP are available on Internet from http://www.hgmp.mrc.ac.uk/~jzhao and http://www.iop.kcl.ac.uk/IoP/Departments/PsychMed/GEpiBSt/software.shtml

Contact: jzhao{at}hgmp.mrc.ac.uk


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