Skip Navigation


Bioinformatics Advance Access originally published online on February 24, 2005
Bioinformatics 2005 21(10):2514-2516; doi:10.1093/bioinformatics/bti350
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (Print PDF) Freely available
Right arrow All Versions of this Article:
21/10/2514    most recent
bti350v2
bti350v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (5)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Choi, K.
Right arrow Articles by Kim, S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Choi, K.
Right arrow Articles by Kim, S.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The Author 2005. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions{at}oupjournals.org

PLATCOM: a Platform for Computational Comparative Genomics

Kwangmin Choi 1, Yu Ma 2, Jeong-Heyon Choi 1 and Sun Kim 1,3,*

1School of Informatics, Indiana University Bloomington, IN 47404, USA
2Department of Computer Science, Indiana University Bloomington, IN 47404, USA
3Center for Genomics and Bioinformatics, Indiana University Bloomington, IN 47404, USA

*To whom correspondence should be addressed.

Motivation: As more whole genome sequences become available, comparing multiple genomes at the sequence level can provide insight into new biological discovery. However, there are significant challenges for genome comparison. The challenge includes requirement for computational resources owing to the large volume of genome data. More importantly, since the choice of genomes to be compared is entirely subjective, there are too many choices for genome comparison. For these reasons, there is pressing need for bioinformatics systems for comparing multiple genomes where users can choose genomes to be compared freely.

Results: PLATCOM (Platform for Computational Comparative Genomics) is an integrated system for the comparative analysis of multiple genomes. The system is built on several public databases and a suite of genome analysis applications are provided as exemplary genome data mining tools over these internal databases. Researchers are able to visually investigate genomic sequence similarities, conserved gene neighborhoods, conserved metabolic pathways and putative gene fusion events among a set of selected multiple genomes.

Availability: http://platcom.informatics.indiana.edu/platcom

Contact: sunkim2{at}indiana.edu; kwchoi{at}indiana.edu


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 BioinformaticsHome page
D. Salgado, G. Gimenez, F. Coulier, and C. Marcelle
COMPARE, a multi-organism system for cross-species data comparison and transfer of information
Bioinformatics, February 1, 2008; 24(3): 447 - 449.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
J. Park, B. Park, K. Jung, S. Jang, K. Yu, J. Choi, S. Kong, J. Park, S. Kim, H. Kim, et al.
CFGP: a web-based, comparative fungal genomics platform
Nucleic Acids Res., January 11, 2008; 36(suppl_1): D562 - D571.
[Abstract] [Full Text] [PDF]

Home page
 BioinformaticsHome page
C. Toft and M. A. Fares
GRAST: a new way of genome reduction analysis using comparative genomics
Bioinformatics, July 1, 2006; 22(13): 1551 - 1561.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.