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Bioinformatics Advance Access originally published online on March 1, 2005
Bioinformatics 2005 21(10):2537-2538; doi:10.1093/bioinformatics/bti331
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© The Author 2005. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions{at}oupjournals.org

Protein structure topological comparison, discovery and matching service

G. M. Torrance 1, D. R. Gilbert 1,*, I. Michalopoulos 2 and D. W. Westhead 2

1Bioinformatics Research Centre, Department of Computer Science, University of Glasgow Glasgow G12 8QQ UK
2School of Biochemistry and Microbiology, University of Leeds Leeds LS2 9JT, UK

*To whom correspondence should be addressed.

Summary: We describe a fold level fast protein comparison and motif matching facility based on the TOPS representation of structure. This provides an update to a previous service at the EBI, with a better graph matching with faster results and visualization of both the structures being compared against and the common pattern of each with the target domain.

Availability: Web service at http://balabio.dcs.gla.ac.uk/tops or via the main TOPS site at http://www.tops.leeds.ac.uk. Software is also available for download from these sites.

Contact: tops{at}brc.dcs.gla.ac.uk


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