Bioinformatics Advance Access originally published online on March 1, 2005
Bioinformatics 2005 21(10):2537-2538; doi:10.1093/bioinformatics/bti331
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Protein structure topological comparison, discovery and matching service
1Bioinformatics Research Centre, Department of Computer Science, University of Glasgow Glasgow G12 8QQ UK
2School of Biochemistry and Microbiology, University of Leeds Leeds LS2 9JT, UK
*To whom correspondence should be addressed.
Summary: We describe a fold level fast protein comparison and motif matching facility based on the TOPS representation of structure. This provides an update to a previous service at the EBI, with a better graph matching with faster results and visualization of both the structures being compared against and the common pattern of each with the target domain.
Availability: Web service at http://balabio.dcs.gla.ac.uk/tops or via the main TOPS site at http://www.tops.leeds.ac.uk. Software is also available for download from these sites.
Contact: tops{at}brc.dcs.gla.ac.uk
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