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Bioinformatics Advance Access originally published online on April 6, 2005
Bioinformatics 2005 21(11):2780-2782; doi:10.1093/bioinformatics/bti412
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© The Author 2005. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions{at}oupjournals.org

ROBIN: a tool for genome rearrangement of block-interchanges

Chin Lung Lu 1,*, Tsui Ching Wang 1, Ying Chih Lin 2 and Chuan Yi Tang 2

1Department of Biological Science and Technology, National Chiao Tung University Hsinchu 300, Taiwan, ROC
2Department of Computer Science, National Tsing Hua University Hsinchu 300, Taiwan, ROC

*To whom correspondence should be addressed.

Summary: ROBIN is a web server for analyzing genome rearrangement of block-interchanges between two chromosomal genomes. It takes two or more linear/circular chromosomes as its input, and computes the number of minimum block-interchange rearrangements between any two input chromosomes for transforming one chromosome into another and also determines an optimal scenario taking this number of rearrangements. The input can be either bacterial-size sequence data or landmark-order data. If the input is sequence data, ROBIN will automatically search for the identical landmarks that are the homologous/conserved regions shared by all the input sequences.

Availability: ROBIN is freely accessed at http://genome.life.nctu.edu.tw/ROBIN

Contact: cllu{at}mail.nctu.edu.tw


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This article has been cited by other articles:


Home page
 Nucleic Acids ResHome page
Y. C. Lin, C. L. Lu, Y.-C. Liu, and C. Y. Tang
SPRING: a tool for the analysis of genome rearrangement using reversals and block-interchanges.
Nucleic Acids Res., July 1, 2006; 34(Web Server issue): W696 - W699.
[Abstract] [Full Text] [PDF]


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