Bioinformatics Advance Access originally published online on June 21, 2005
Bioinformatics 2005 21(16):3448-3449; doi:10.1093/bioinformatics/bti551
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BiNGO: a Cytoscape plugin to assess overrepresentation of Gene Ontology categories in Biological Networks
Department of Plant Systems Biology, Flanders Interuniversity Institute for Biotechnology (VIB), Ghent University Technologiepark 927, B-9052, Ghent, Belgium
*To whom correspondence should be addressed.
Summary: The Biological Networks Gene Ontology tool (BiNGO) is an open-source Java tool to determine which Gene Ontology (GO) terms are significantly overrepresented in a set of genes. BiNGO can be used either on a list of genes, pasted as text, or interactively on subgraphs of biological networks visualized in Cytoscape. BiNGO maps the predominant functional themes of the tested gene set on the GO hierarchy, and takes advantage of Cytoscape's versatile visualization environment to produce an intuitive and customizable visual representation of the results.
Availability: http://www.psb.ugent.be/cbd/papers/BiNGO/
Contact: martin.kuiper{at}psb.ugent.be
Received on May 18, 2005; revised on June 13, 2005; accepted on June 17, 2005
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